JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES

Article

Journal of Clinical and Biomedical Sciences

Year: 2015, Volume: 5, Issue: 2, Pages: 89-91

Short communications/brief reports

A Study on Renal Function Tests and its Correlation with Blood Glucose and eGFR in Newly Diagnosed Type 2 Diabetes Mellitus

Abstract

Background: Elevated values of renal function tests are associated with type 2 diabetes mellitus. But there are studies that found that the levels of creatinine and uric acid are low in cases of diabetes mellitus. Comparative studies related to serum renal function tests with eGFR and blood glucose in type 2 DM is less. Hence the study was undertaken to study the RFT and its correlation with blood glucose and eGFR in type 2 DM. Materials and Methods: 25 newly diagnosed cases of type 2 diabetes mellitus and 25 healthy controls were studied. Results: Mean serum urea levels were 25.80±6.75 mg/dL in controls and 34.08±9.62 in cases, which was statistically significant. Mean serum creatinine and uric acid values were also statistically significant (p=0.0002). Significant positive correlation was found between FBS (p<0.001) and PPBS (p<0.0001) with the eGFR and renal function tests in both cases and controls. Conclusion: our study shows urea, creatinine and uric acid levels are towards higher reference limits in cases compared to controls.

Key-words: eGFR, FBS, PPBS, RFT, uric acid

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