JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES

Article

Journal of Clinical and Biomedical Sciences

Year: 2013, Volume: 3, Issue: 2, Pages: 85-89

Case Report

Unilateral Proptosis as the initial presentation of Multiple Myeloma

Received Date:02 January 2013, Accepted Date:04 February 2013, Published Date:06 May 2013

Abstract

A 75 year lady presented with the complaints of double vision on up gaze since 1 year and gradually progressive painless protrusion of the left eye since 2 months. There was a history of repeated admission to the hospital in past 1 year for weakness. On systemic examination patient had pallor, pedal edema and a borderline splenomegaly. Ocular examination revealed eccentric proptosis. CT scan of head and orbit showed an isointense ill-defined mass in superior anterio-lateral extraconal space extending to the medial side which was eroding the fronto-zygomatic bones. Fine Needle aspiration cytology showed binucleate plasma cells and plasma blasts suggestive of multiple myeloma. Serum electrophoresis showed 2 abnormal bands of paraproteins in the gamma region. Though uncommon, proptosis could be the initial presentation of multiple myeloma. A high clinical suspicion helps us to make a diagnosis of multiple myeloma. Early diagnosis and timely treatment would help to prolong the patient's life and to improve quality of life.

Key words: Multiple myeloma, Unilateral proptosis, Plasma cell

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