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  <front>
    <journal-meta id="journal-meta-469d58c147914c61b2e5b314fef32850">
      <journal-id journal-id-type="nlm-ta">Sciresol</journal-id>
      <journal-id journal-id-type="publisher-id">Sciresol</journal-id>
      <journal-id journal-id-type="journal_submission_guidelines">https://www.jcbsonline.ac.in/</journal-id>
      <journal-title-group>
        <journal-title>Journal of Clinical and Biomedical Sciences</journal-title>
      </journal-title-group>
      <issn publication-format="electronic">2319-2453</issn>
      <issn publication-format="print"/>
    </journal-meta>
    <article-meta id="article-meta-85a00a7cbc3a446ebb5f9f4c95758a3c">
      <article-id pub-id-type="doi">10.58739/jcbs/v13i2.23.26</article-id>
      <article-categories>
        <subj-group>
          <subject>Case Report</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title id="article-title-d801e73872e1436c9155707645168efa">
          <bold id="strong-fd8f4d97053e4637b94a88333b274816">Intraventricular </bold>
          <bold id="strong-4e18a4002191494aa4107881a6271f0e">Neurocystecercosis</bold>
          <bold id="strong-fd0691dc76dc4e62be7021c9a8fd5f34"> </bold>
          <bold id="strong-0e84ef113f194e2eb5fdef115194eb48">with Psychiatry Manifestations</bold>
        </article-title>
        <alt-title alt-title-type="right-running-head">Neurocystecercosis with psychiatry manifestations</alt-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name id="name-538c11bda3a240c8856af482898bef78">
            <surname>Anitha</surname>
            <given-names>A</given-names>
          </name>
          <xref id="xref-072466ce2555417dafea4d5119ad7cbe" rid="aff-187e41ba628344efa8123e37a5061477" ref-type="aff">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <contrib-id contrib-id-type="orcid"/>
          <name id="n-cb5a145ac3f0">
            <surname>Kruthi</surname>
            <given-names>P</given-names>
          </name>
          <xref id="x-3c69404e2174" rid="aff-3f853c4ff7c14ebca3851a46040b1f07" ref-type="aff">2</xref>
        </contrib>
        <contrib contrib-type="author" corresp="yes">
          <contrib-id contrib-id-type="orcid"/>
          <name id="n-8d1dab01dbe0">
            <surname>Prabhakar</surname>
            <given-names>K</given-names>
          </name>
          <email>drprabhakark@yahoo.in</email>
          <xref id="x-cebe37010214" rid="aff-587284f3819e474a994887dc33d25bc0" ref-type="aff">3</xref>
        </contrib>
        <aff id="aff-187e41ba628344efa8123e37a5061477">
          <institution>Associate Professor, Sri Devaraj Urs Medical College</institution>
          <addr-line>Tamaka, Kolar, Karnataka</addr-line>
          <country country="IN">India</country>
        </aff>
        <aff id="aff-3f853c4ff7c14ebca3851a46040b1f07">
          <institution>Postgraduate, Sri Devaraj Urs Medical College</institution>
          <addr-line>Tamaka, Kolar, Karnataka</addr-line>
          <country country="IN">India</country>
        </aff>
        <aff id="aff-587284f3819e474a994887dc33d25bc0">
          <institution>Professor, Sri Devaraj Urs Medical College</institution>
          <addr-line>Tamaka, Kolar, Karnataka</addr-line>
          <country country="IN">India</country>
        </aff>
      </contrib-group>
      <volume>13</volume>
      <issue>2</issue>
      <fpage>59</fpage>
      <permissions>
        <copyright-year>2023</copyright-year>
      </permissions>
      <abstract id="abstract-abstract-title-3e38d0bdc36c4d85b58ce2066d79018b">
        <title id="abstract-title-3e38d0bdc36c4d85b58ce2066d79018b">Abstract</title>
        <p id="paragraph-960edf120279440d90d4bdf56a668018">Neurocysticercosis (NCC)is one of the common parasitic infection of the central nervous system, caused by tenia solium. We present here a case of 19-year-old female presented with partial hanging, on CT brain incidentally found to have asymmetric ectasia of right lateral ventricle, for which MRI was done revealed - intraventricular neurocysticercosis causing obstructive hydrocephalus. Extra parenchymal neurocysticercosis can occur in ventricles, sub arachnoid space, spine and eyes. A recent study reported an overall frequency of subarachnoid cysts in 2%, ventricular cysts in 6%, and hydrocephalus in 16% of NCC cases. It may be associated with any neurological sign and symptom. Focal neurological deficits have been recognized in one-third of symptomatic patients. Motor deficits, involuntary movements, Parkinsonism, language disturbances, sensory deficits may occur in some patients. Psychiatric disorders may mark the evolution of hydrocephalus, As in our case, patient with unilateral hydrocephalus presented with alleged history of hanging , it is important to rule out organic brain diseases in all cases with psychiatry manifestations.</p>
        <p id="p-1d9efb014a64"/>
      </abstract>
      <kwd-group id="kwd-group-ba7b1a888416455baefaa1f1e7431b04">
        <title>Keywords</title>
        <kwd>Neurocysticercosis</kwd>
        <kwd>Hydrocephalus</kwd>
        <kwd>Psychiatry disorder</kwd>
      </kwd-group>
      <funding-group>
        <funding-statement>None</funding-statement>
      </funding-group>
    </article-meta>
  </front>
  <body>
    <sec>
      <title id="title-47d624db658a4b5c8d91a810dc2f1b82">Introduciton</title>
      <p id="paragraph-a4699575ef47476683a8d76cf0e323a5">Neurocysticercosis (NCC) is a common parasitic infection affecting central nervous system and is prevalent in Asia and Africa. It affects the brain parenchyma, subarachnoid spaces and ventricles. Prevalence of human taeniasis varies from 2.5% to 8.0% in India according to various studies data. Neurocysticercosis causing epilepsy is about one per 1000 population. It is a parasitic infection by Taenia solium. Humans being only definitive host and disease is seen when the human beings ingest egg present in food contaminated with feces of the tapeworm. Neurocysticercosis is classified based on its location- subarachnoid-cisternal space, parenchymal, ventricles, spinal and mixed form. These different forms can co-exist. Parenchymal is the most common location. <xref id="xref-d69d0342a6404af5945b4bc8e7afe72b" rid="R200439428515124" ref-type="bibr">1</xref></p>
      <p id="paragraph-4f809d6c811e47949f549bfe3e4b6974">It may be associated with any neurological sign and symptom. Focal neurological deficits have been recognized in one-third of symptomatic patients. Motor deficits, involuntary movements, Parkinsonism, language disturbances, sensory deficits may occur in some patients.3% of infected people can present with strokes. They also can present with features of raised intracranial pressure when hydrocephalus occurs. <xref id="xref-9d3479af398d4d8ca36523c20280c775" rid="R200439428515118" ref-type="bibr">2</xref></p>
      <p id="paragraph-190bae1bba0e4fc0a21a6e806f8de7d9">Hydrocephalus is a neurological problem caused by excessive accumulation of cerebrospinal fluid(CSF) due to abnormal secretion, circulation and absorption. It is one of the cause for reversible dementia, but role psychiatry manifestations is yet to delineate. <xref id="xref-971759389b8b4e25924588aacfd24f58" rid="R200439428515126" ref-type="bibr">3</xref> When hydrocephalus occurs due to any infective agent, it is termed as post-infective hydrocephalus (PIH). <xref id="xref-cf47ff8124b04f47ae22fbf004b22128" rid="R200439428515119" ref-type="bibr">4</xref></p>
      <p id="paragraph-cf6e3b2d6d19477c9bc7b99f2a20e9c1">Hereby presenting a rare case of neurocysticercosis presented with unilateral hydrocephalus.</p>
    </sec>
    <sec>
      <title id="t-b41144330276">
        <bold id="strong-0677df4f39a442d791671844e068776f">Case Report </bold>
      </title>
      <p id="paragraph-8673946081344e908cc0c4cd81d90f05">A 19-year-old female presented to emergency department with alleged history of partial hanging and one episode of generalized tonic clonic seizures. Past history of psychotic episodes was given by patient attenders. Neurological Examination was unremarkable.</p>
      <p id="paragraph-c7fff56c50fb47829343678ec35534f3">CT Brain imaging done showed asymmetric ectasia of right lateral ventricle. </p>
      <p id="paragraph-d03f24ca3f4941dfb76cc26bd36257ae">MRI Brain revealed multiple intraventricular mobile cysts with calcified scolex with occasional obstruction in the right lateral ventricle. Asymmetric dilation of the right lateral ventricle<bold id="strong-2158b2180b924b90a5e1b0ed8876e9b6">.</bold></p>
      <fig id="figure-44fc81c21574468dbc8dc72503383f56" orientation="portrait" fig-type="graphic" position="anchor">
        <label>Figure 1 </label>
        <caption id="caption-3ba81c6fb46c4114a51e3fb84abda65e">
          <title id="title-cc3ac2322b77403194468d91b3ed7451">Radiographic images</title>
        </caption>
        <graphic id="graphic-7e1a8b1847244c7a9834c09eece7447d" xlink:href="https://s3-us-west-2.amazonaws.com/typeset-prod-media-server/7c990305-adb8-45c9-b6cd-5152bba9a482image1.png"/>
      </fig>
    </sec>
    <sec>
      <title id="title-72d9b43e94c746a781e9ca38946e7b96">Discussion</title>
      <p id="paragraph-150cc02ad89c49ac905bcff527fd14b6">Extra parenchymal neurocysticercosis is seen in ventricles, sub arachnoid space, spine and eyes. A study reported an overall frequency of subarachnoid cysts in 2%, ventricular cysts in 6%, and hydrocephalus in 16% of NCC cases. <xref id="xref-91a62786822b4c83b552650c2b3e693b" rid="R200439428515127" ref-type="bibr">5</xref> Clinical manifestations and CSF findings are similar to the more common tuberculous and fungal meningitis. <xref rid="R200439428515117" ref-type="bibr">6</xref>, <xref rid="R200439428515116" ref-type="bibr">7</xref></p>
      <p id="paragraph-fd9189163ce147cfa31af0a5b3518c1c">In intraventricular neurocysticercosis, the larvae reach the cerebral ventricles via the choroid plexus and cause symptoms due to hydrocephalus. Intraventricular neurocysticercosis commonly presents with acute obstructive hydrocephalus. Headache is the most common manifestation.</p>
      <p id="paragraph-6c868d0dc0ba4cda8586633f3a832504">CSF findings are similar to fungal or tubercular meningitis with lymphocytic pleocytosis, elevated protein concentration. In one series of cysticercal meningoencephalitis, confusion with tubercular meningitis was present in 61.5% cases. <xref id="xref-c777a5c0d6284bf0adc479a78c6aa8c0" rid="R200439428515120" ref-type="bibr">8</xref></p>
      <p id="paragraph-66d21e65350443ddb1b315e2a9c20747">Various therapeutic modalities include antihelminthic medication, microneurosurgical removal, ventriculoperitoneal shunting, and endoscopic management. <xref id="x-c06acddfbee0" rid="R200439428515121" ref-type="bibr">9</xref></p>
      <p id="paragraph-c1f7831c15504d75871d13b2cb4e074c">In our present case psychiatric symptoms can be manifestation of hydrocephalus. As observed in a study,these patients may benefit from treatment of hydrocephalus to improve psychiatry symptoms.<xref id="xref-d180515f375d469cb73c6c02676702d3" rid="R200439428515120" ref-type="bibr">8</xref> Psychiatric disorders may mark the evolution of hydrocephalus. <xref rid="R200439428515125" ref-type="bibr">10</xref>, <xref rid="R200439428515126" ref-type="bibr">3</xref><sup id="superscript-f8bca7b7cf85414f95c8e3b766a8358a"> </sup>As in our case, patient with unilateral hydrocephalus presented with alleged history of hanging , it is needed to rule out organic brain diseases in all cases with psychiatry manifestations.</p>
    </sec>
  </body>
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