Degenerative and Protective effects of Nicotine in Neurodegenerative diseases

Sadhu Lokanadham; Usha Kothandaraman

doi:10.58739/jcbs/v04i4.3

Article

Degenerative and Protective effects of Nicotine in Neurodegenerative diseases

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Journal of Clinical and Biomedical Sciences

DOI: 10.58739/jcbs/v04i4.3

Year: 2014, Volume: 4, Issue: 4, Pages: 373

Review Article

Degenerative and Protective effects of Nicotine in Neurodegenerative diseases

Sadhu Lokanadham^*1, Usha Kothandaraman²

¹Department of Anatomy, Bharath University, Chennai, Tamilnadu.
²Department of Anatomy, ESIC Medical College & PGIMSR, Chennai, Tamilnadu.

*Corresponding Author
Email Id: loka.anatomy@yahoo.com

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Aging is the greatest risk factor for neurodegenerative diseases. Progressive loss of structure or function of neurons, including death of neurons considered as neurodegenation. Cell death in neurodegeneration is due to apoptosis and most commonly through the intrinsic mitochondrial pathway genetic mutations. Neurodegenerative (ND) Diseases are chronic, progressively debilitating, and incurable. There are different types of neurodegenerative diseases like Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD). Among different types of Neurodegenerative diseases, Alzheimer’s disease appears to be the most common. The disabling effects for individuals with Neurodegenerative diseases may continue for years or even decades. The prevalence of Neurodegenerative diseases has increased globally, most noticeably in the aging populations of the developed world.