Journal of Clinical and Biomedical Sciences
DOI: 10.58739/jcbs/v16i2.25.143
Year: 2026, Volume: 16, Issue: 2, Pages: 16-24
Original Article
Pradip Saha1, Pradip Ghoshal1, Anubhav Prakash1*, Goutam Datta1
1IPGMER & SSKMH, Kolkata, West Bengal, India.
*Corresponding Author
Email: [email protected]
Received Date:26 March 2025, Accepted Date:03 March 2026, Published Date:15 June 2026
This study investigates the role of various echocardiographic parameters in assessing right ventricular (RV) function in patients with inferior wall myocardial infarction (IWMI) and right ventricular myocardial infarction (RVMI). The primary objective is to evaluate the use of pulmonary regurgitation pressure half-time (PRPHT) and right ventricular global longitudinal strain (RVGLS) as indicators of RV dysfunction and prognostic markers for adverse in-hospital outcomes. The study is a prospective observational cross-sectional analysis conducted at the public sector apex institute in eastern India, involving 155 patients diagnosed with acute IWMI/RVMI. Patients underwent a comprehensive evaluation followed by a three-month post-treatment follow-up. Echocardiographic parameters were measured. The study’s findings suggest significant correlations between these parameters, highlighting their interdependence in evaluating RV function. The results indicate that PRPHT and RVGLS can serve as reliable markers for assessing RV dysfunction. The results also indicate that PRPHT could serve as a valuable prognostic indicator in patients with PRPHT ≤ 100 ms. This study also suggests that PRPHT has no significant correlation with in-hospital outcome especially in patients with PRPHT >100ms. This study also suggests that RVGLS bears no value in predicting in-hospital outcomes. The findings of this study also suggest that negative RVGLS are well correlated with other standard echocardiographic measures of RV dysfunction viz. TAPSE and FAC. The study concludes that integrating PRPHT with traditional markers viz. TAPSE, RVFAC, and RVGLS provides a comprehensive assessment of RV function, enabling better identification of patients at risk of adverse outcomes following IWMI/RVMI. This study also suggests that PRPHT has no significant correlation with in-hospital outcome especially in patients with PRPHT >100ms. However, the study acknowledges limitations such as the small sample size and the need for further research to confirm these findings and establish PRPHT’s clinical utility as as a prognostic tool. It was also noted that patients with PRPHT values < 90, TAPSE of less than 10, FAC of less than 28% and RVGLS value of less than (-12) were able to predict in-hospital outcome in patients of IWMI/RVMI. The findings of present study also suggests that interventions in IWMI/RVMI have good outcomes at 3 month follow-up.
Keywords: RVMI, IWMI, Echocardiography, PRPHT, RVGLS, TAPSE
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Published By Sri Devaraj Urs Academy of Higher Education, Kolar, Karnataka
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