Chromosomes to Genes:  Implications of Array Comparative Genomic Hybridization  (array-CGH) in Medical Practice

Krishna Murthy D S

doi:10.58739/jcbs/v01i3.9

Article

Chromosomes to Genes: Implications of Array Comparative Genomic Hybridization (array-CGH) in Medical Practice

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Journal of Clinical and Biomedical Sciences

DOI: 10.58739/jcbs/v01i3.9

Year: 2011, Volume: 1, Issue: 3, Pages: 91-96

Review Article

Chromosomes to Genes: Implications of Array Comparative Genomic Hybridization (array-CGH) in Medical Practice

Krishna Murthy D S

Genomics and Central Research Laboratory, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, Karnataka

*Corresponding Author
Email: [email protected]

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

HUMAN GENOME Every cell has an estimated 30,000 genes that function in an orderly manner and maintain the complex cellular functions such as DNA replication, repair and gene expression. Each and every cell in the human body carries an genetic information in DNA, of which genes are specific parts that encode for proteins to allow b i o l o g i c a l a c t i v i t y t o o c c u r. T h e activity/inactivity of a gene(s) can be measured using microarrays, which can probe tens of thousands of genes simultaneously.