JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES

Abstract

Magnesium is an important macromineral. Major amount of magnesium is present in the bones. Magnesium absorption takes place at the small intestine and magnesium levels are maintained by the kidneys. Magnesium is a fundamental mineral in the mammalian cells. Magnesium acts as a co-factor for many enzymes, especially enzymes involved in carbohydrate and lipid metabolism. Magnesium is necessary for muscle contraction by acting as a calcium antagonist, cellular proliferation, apoptosis, immune response, etc. Now a days hypomagnesemia is very commonly seen condition associated with predominant diseases like diabetes, hypertension, cardiovascular diseases, obesity, etc. Several authors have reported that low serum magnesium levels, insulin resistance and hyperlipidemia are interrelated. Hypomagnesemia may play an causative role in the development of diabetes, oxidative stress, thrombosis, atherosclerosis, etc. Hence magnesium importances should be highlighted in the research field.

Keywords: hypomagnesemia, hyperlipidemia and atherosclerosis