JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES

Abstract

Background: Hyperuricemia is associated with type 2 diabetes mellitus. But there are studies that found that the levels of uric acid are low in cases of diabetes mellitus. Comparative studies related to serum uric acid levels with eGFR and blood glucose in type 2 diabetes mellitus is less. Hence the study was undertaken to study the serum uric acid levels and its correlation with blood glucose and eGFR in type 2 diabetes mellitus. Materials & Methods: 40 diagnosed cases of type II diabetes mellitus and 40 healthy controls were studied. Results: The mean uric acid levels were 4.5±1.1 in cases and 4.6±1.1 in controls,which was not statistically significant. Significant negative correlation was found between uric acid(0.006) and eGFR in both cases and controls. Significant positive correlation was found between FBS (p = 0.005) and PPBS (P = 0.04) with the eGFR in cases and between FBS and PPBS in cases and controls. Uric acid correlation with FBS and PPBS is not significant in both cases and controls. Conclusion: our study shows uric acid levels are towards lower reference limits in type 2 diabetes mellitus when compared to controls.

Key words: eGFR, FBS, PPBS, uric acid