Journal of Clinical and Biomedical Sciences
Year: 2021, Volume: 11, Issue: 1, Pages: 39-41
Case Report
Kalyani R1*,Varsha Shree Rajanna2,Ankit Ananad3, Shashirekha CA4
1. Professor & HOD, Department of Pathology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Tamaka, Kolar.
2. Resident, Department of Pathology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Tamaka, Kolar.
3. Post graduate, Department of Pathology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Tamaka, Kolar.
4. Associate Professor, Department of Surgery, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Tamaka, Kolar..
*Corresponding Author
E-mail: [email protected]
Mobile No: 9448402775
Metaplastic breast carcinoma (MBC) is rare and distinct histological type of breast cancer. It consists of features of both epithelial & mesenchymal type in a single tumor. It is highly aggressive tumor having poor prognosis.
We present three cases. In first case, 35 year female presented with a lump in left breast for two months. Microscopy showed well differentiated squamous cell carcinoma with 2/10 lymph nodes showing tumor deposits. In second case, 56 year female presented with lump in left breast for six months. Microscopy showed oval cells with prominent nucleolus, spindle cells, osteoclast type giant cells, focal areas of squamous cell carcinoma with 1/ 7 lymph node involvement. In third case, 52 year female presented with lump in right breast for six months. Microscopy showed squamous cell variant of metaplastic carcinoma with no tumour deposits in five lymph nodes retrieved. Metaplastic breast carcinoma has a diverse clinical behaviour, variable histology and poor prognosis.
Keywords: Breast, breast cancer, metaplastic carcinoma
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