JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES

Abstract

Biomarkers (Biological Markers) in simple words are a broad subcategory of medical signs that is, objective indications of medical state observed from outside the patient which can be measured accurately and reproducibly. In the past biomarkers included study of pulse, blood pressure, basic chemistries, basic labora-tory investigations of blood and tissues. Re-cently National Institute of Health and Food and Drug administration biomarker Working Group (2015) defined biomarker as “A defined characteristic that is measured as an indicator of normal biological processes, pathogenic pro-cesses, or responses to an exposure or inter-vention, including therapeutic interventions