![A Comprehensive Review on Medicinal Value and Pharmacological Profile of Simarouba Amara [Abul]](https://sciresol.s3.us-east-2.amazonaws.com/srs-j/JCBS/Image/Vol-15/Issue-4/PH_101.png)
Journal of Clinical and Biomedical Sciences
DOI: 10.58739/jcbs/v15i4.24.101
Year: 2025, Volume: 15, Issue: 4, Pages: 306-312
Review Article
Rajani Vallepu1*, Divya Kodiganti1, Nagaraju C N2, Savitha P N1
1Department of Pharmacology, SKU College of Pharmaceutical sciences, Ananthapuramu, Andhra Pradesh, 515003, India.
2Department of Biochemistry, Yogivemana University, YSR Kadapa, Andhra Pradesh, 516005, India.
*Corresponding Author
Email: [email protected]
Received Date:14 August 2024, Accepted Date:27 September 2025, Published Date:31 December 2025
Simarouba amara is a tree species from the Simaroubaceae family, native to the rainforests, savannahs, and Caribbean regions of Central and South America. This study provides a comprehensive review of the medicinal and pharmacological profile of S. amara. The plant's leaves and bark have been traditionally used to treat various ailments, including malaria, diarrhea, and dysentery 1. Phytochemical analysis reveals the presence of quassinoids, a class of triterpenes, which are responsible for the plant's therapeutic properties. Some of them are Ailanthinone, glaucarubinone, and holacanthone which are the principle biologically active phytochemical constituents present in S. amara. It possesses therapeutic qualities; Pharmacologically have been employed as an “anthelminthic, anticancer, anti-inflammatory, antiviral, anorectic, tonic, insecticide, antimalarial, antimicrobial, anti-amoebic, hepatoprotective, analgesic, antipyretic, antidiarrheal, anti-bacterial, gastroprotective, antileukemic, astringent, febrifuge and skin hydrator”.
Keywords: <i>Simarouba amara</i>, Pharmacological activities, Phytochemical analysis, Medicinal value
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Published By Sri Devaraj Urs Academy of Higher Education, Kolar, Karnataka
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