A Review on Medicinal Value and Pharmacological Profile of Mussaenda erythrophylla

Savitha P N; Rajani Vallepu  lowast; Nagaraju C; Divya K

doi:10.58739/jcbs/v15i3.24.98

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Journal of Clinical and Biomedical Sciences

DOI: 10.58739/jcbs/v15i3.24.98

Year: 2025, Volume: 15, Issue: 3, Pages: 156-162

Review Article

A Review on Medicinal Value and Pharmacological Profile of Mussaenda erythrophylla

Savitha P N¹, Rajani Vallepu^1∗, Nagaraju C², Divya K¹

¹Department of Pharmacology, SKU College of Pharmaceutical Sciences, Ananthapuramu, 515003, Andhra Pradesh, India
²Department of Biochemistry, Yogi Vemana University, YSR Kadapa, 516003, Andhra Pradesh, India

*Corresponding Author
Email: [email protected]

Received Date:13 August 2024, Accepted Date:26 June 2025, Published Date:22 September 2025

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Mussaenda erythrophylla, a botanical treasure, has revealed numerous pharmacological potentials warranting scientific investigation. The hydroalcoholic extract of its leaves demonstrated dose-dependent analgesic, anti-inflammatory, and antipyretic activities. Notably, the leaf extract exhibited robust antioxidant activity, comparable to vitamin C, as evidenced by DPPH and NO assays. Methanolic extracts of the plant showed promising in vitro anthelmintic activity against earthworms. Additionally, root extracts in chloroform and ethanol significantly increased urine volume. Methanolic and ethyl acetate extracts of the plant protected against CCl4-induced hepatotoxicity in rats, as indicated by decreased serum enzyme levels. The plant extracts also demonstrated anti-arthritic properties through proteinase inhibition and denaturation assays. Ethanolic leaf extract showed potent anti-plasmodial activity against P. falciparum, with minimal toxicity. Furthermore, the leaf extract effectively inhibited carbon steel corrosion in a 1M HCl solution. Phytochemical analysis of floral extracts revealed the presence of steroids and triterpenoids.

Keywords: Herbal remedy, Analgesic, antioxidant, Anti-arthritic, Anti-plasmodial, Corrosion inhibition

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