JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES

Article

Journal of Clinical and Biomedical Sciences

Year: 2025, Volume: 15, Issue: 4, Pages: 319-327

Systematic Review

Therapeutic Potential of Banana Pseudo- Stem Extracts: A Systematic Review and Meta-Analysis of Antioxidant, Anti- Inflammatory, Antimicrobial, and Anti- Urolithiatic Properties with Risk of Bias Assessment

Received Date:17 November 2024, Accepted Date:11 January 2025, Published Date:31 December 2025

Abstract

Banana pseudo-stem, a farming waste, may contain bioactive compounds with therapeutic properties. Due to its antioxidant, anti-inflammatory, antibacterial, and anti-urolithiatic properties, banana pseudo-stem extracts may help manage chronic diseases, infections, and kidney stones, according to recent research A complete synthesis of research must evaluate banana pseudo-stem extract efficacy and safety. Objectives: This systematic review and meta-analysis analyse banana pseudo-stem extracts' antioxidant, anti-inflammatory, antibacterial, and anti-urolithiatic properties. A risk of bias evaluation will evaluate the evidence's quality and reliability. Method: PubMed, Scopus, and Web of Science for banana pseudo-stem extract medical studies. Randomised controlled trials, cohort studies, case-control studies, and preclinical animal studies qualify. Two independent reviewers will examine publications, extract data, and assess bias using the Cochrane Risk of Bias tool for RCTs and the Newcastle-Ottawa Scale for observational studies. Pooled effect sizes will be derived from quantitative data using random-effects meta-analysis. Subgroup analyses will use extraction, dosage, and study population. We will use the I² statistic to quantify heterogeneity and conduct sensitivity experiments as appropriate. Result: Antioxidant capacity, inflammatory marker lowering, antibacterial capabilities, and anti-urolithiatic potential (e.g., urinary oxalate and crystal count) are key outcomes. Secondary outcomes of banana pseudo-stem extract treatment include safety, adverse events, and quality of life. Conclusion: This review will synthesise banana pseudo-stem extracts' therapeutic effects for future study and clinical use. Research will promote banana pseudo-stem as a plant-based therapy and identify gaps.

Keywords: Banana pseudo-stem, Therapeutic potential, Antioxidant activity, Anti-inflammatory effects, Antimicrobial properties, Anti-urolithiatic effects, Bioactive compounds, Herbal medicine, Chronic disease management, Sustainable healthcare, Traditional remedies

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Copyright

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Published By Sri Devaraj Urs Academy of Higher Education, Kolar, Karnataka

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